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Article

Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutations.

Familial cancer - 1 Sept 2012

de Bruin Monique A, Kwong Ava, Goldstein Benjamin A, Lipson Jafi A, Ikeda Debra M, McPherson Lisa, Sharma Bhavna, Kardashian Ani, Schackmann Elizabeth, Kingham Kerry E, Mills Meredith A, West Dee W, Ford James M, Kurian Allison W

Abstract excerpt

The prevalence and penetrance of BRCA1 and BRCA2 (BRCA1/2) mutations may differ between Asians and whites. We investigated BRCA1/2 mutations and cancer risk factors in a clinic-based sample. BRCA1/2 mutation carriers were enrolled from cancer genetics clinics in Hong Kong and California according to standardized entry criteria. We compared BRCA mutation position, cancer history, hormonal and reproductive...

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Identifiers

PMID: 22638769
DOI: 10.1007/s10689-012-9531-9

Genes

BRCA1
BRCA2
TOX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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