Article
State of the science: an update on renal cell carcinoma.
Molecular cancer research : MCR - 1 Jul 2012
Jonasch Eric, Futreal P Andrew, Davis Ian J, Bailey Sean T, Kim William Y, Brugarolas James, Giaccia Amato J, Kurban Ghada, Pause Armin, Frydman Judith, Zurita Amado J, Rini Brian I, Sharma Pam, Atkins Michael B, Walker Cheryl L, Rathmell W Kimryn
Abstract excerpt
Renal cell carcinomas (RCC) are emerging as a complex set of diseases that are having a major socioeconomic impact and showing a continued rise in incidence throughout the world. As the field of urologic oncology faces these trends, several major genomic and mechanistic discoveries are altering our core understanding of this multitude of cancers, including several new rare subtypes of renal cancers. In this...
Topics
- Carcinoma, Renal Cell
- Epigenesis, Genetic
- Extracellular Matrix
- Gene Expression Regulation, Neoplastic
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit
- Molecular Targeted Therapy
- Mutation
- Translational Research, Biomedical