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Genomics of Renal Cell Cancer: The Biology Behind and the Therapy Ahead

15 Jan 2007

Abstract excerpt

Renal cell cancer (RCC) is the most lethal of the urological cancers and accounts for 3% of all adult malignancies. Despite numerous recent advances in diagnostic imaging, surgical therapy, and basic molecular understanding, many patients still experience metastatic disease. For metastatic disease patients, response rates to conventional therapies rarely exceed 15% to 25% and are associated with serious adverse...

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PMID: 17255294
DOI: 10.1158/1078-0432.ccr-06-1867

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