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Article

Gowinda: unbiased analysis of gene set enrichment for genome-wide association studies.

Bioinformatics (Oxford, England) - 1 Aug 2012

Kofler Robert, Schlötterer Christian

Abstract excerpt

SUMMARY: An analysis of gene set [e.g. Gene Ontology (GO)] enrichment assumes that all genes are sampled independently from each other with the same probability. These assumptions are violated in genome-wide association (GWA) studies since (i) longer genes typically have more single-nucleotide polymorphisms resulting in a higher probability of being sampled and (ii) overlapping genes are sampled in clusters....

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PMID: 22635606
DOI: 10.1093/bioinformatics/bts315
PMCID: PMC3400962

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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