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Article

The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.

Molecular cell - 25 May 2012

Nakahara Kanae, Ohkuni Aya, Kitamura Takuya, Abe Kensuke, Naganuma Tatsuro, Ohno Yusuke, Zoeller Raphael A, Kihara Akio

Abstract excerpt

Sphingosine 1-phosphate (S1P) functions not only as a bioactive lipid molecule, but also as an important intermediate of the sole sphingolipid-to-glycerolipid metabolic pathway. However, the precise reactions and the enzymes involved in this pathway remain unresolved. We report here that yeast HF...

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Identifiers

PMID: 22633490
DOI: 10.1016/j.molcel.2012.04.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22633490-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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