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Article

Comparison of chromosome aberration frequency and small-colony TK-deficient mutant frequency in L5178Y/TK(+/-)-3.7.2C mouse lymphoma cells.

Mutagenesis - 1 Nov 1990

Moore M M, Doerr C L

Abstract excerpt

The L5178Y/TK(+/-)-3.7.2C mouse lymphoma assay is used to quantitate the induction of thymidine kinase (TK)-deficient mutants. The mutants detected in the assay form colonies that can be distinguished as large or small. The induction of small-colony mutants has been associated with the induction of chromosome mutations. In the present paper, we compare the analysis of induced small-colony TK mutants with gross...

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Identifiers

PMID: 2263219
DOI: 10.1093/mutage/5.6.609

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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