Article
Molecular aspects of chemical mutagenesis in L5178Y/tk +/- mouse lymphoma cells.
Mutagenesis - 1 Mar 1990
Clive D, Glover P, Applegate M, Hozier J
Abstract excerpt
Southern blot analyses were performed on DNA from at least 10 large and 10 small colony thymidine kinase-deficient (tk -/-) mutants induced by each of 10 mutagens [2-amino-N6-hydroxyadenine (AHA), ethyl methanesulfonate (EMS), methyl methanesulfonate, 2-acetylaminofluorene, methotrexate, caffeine...
Topics
- Animals
- Chromosome Mapping
- DNA
- Hypoxanthine Phosphoribosyltransferase
- Leukemia L5178
- Leukemia, Experimental
- Mice
- Mutagenicity Tests
- Mutagens
- Mutation
- Thymidine Kinase
- Tumor Cells, Cultured
