Article
The 9p21 coronary artery disease locus and kidney dysfunction in patients with Type 2 diabetes mellitus.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Dec 2012
De Cosmo Salvatore, Prudente Sabrina, Lamacchia Olga, Lucchesi Daniela, Shah Hetal, Mendonca Christine, Pucci Laura, Mercuri Luana, Gervino Ernest V, Hauser Thomas H, Bailetti Diego, Penno Giuseppe, Cignarelli Mauro, Doria Alessandro, Trischitta Vincenzo
Abstract excerpt
BACKGROUND: We investigated whether the coronary artery disease (CAD) locus on chromosome 9p21 (as represented by single nucleotide polymorphism rs2383206) is associated with low estimated glomerular filtration rate (eGFR) or increased urinary albumin excretion in patients with Type 2 diabetes mellitus (T2DM). METHODS: Four samples, including a total of 3167 patients, were studied. The presence of low eGFR (<60...
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