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A unifying model for the role of the ATG8 system in autophagy

1 Jun 2022

Abstract excerpt

The formation of autophagosomes and their fusion with lysosomes are key events that underpin autophagic degradation of cargoes. The core ATG8 system, which consists of the ATG8 family of ubiquitin-like proteins and the machineries that conjugate them onto autophagosomal membranes, are among the most-studied autophagy components. Despite the research focus on the core ATG8 system, there are conflicting reports...

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PMID: 35665638
DOI: 10.1242/jcs.258997

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