Article
Double duty of Atg9 self-association in autophagosome biogenesis.
Autophagy - 1 Apr 2009
He Congcong, Baba Misuzu, Klionsky Daniel J
Abstract excerpt
The understanding of the membrane flow process during autophagosome formation is essential to illuminate the role of autophagy under various disease-causing conditions. Atg9 is the only identified integral membrane protein required for autophagosome formation, and it is thought to cycle between the membrane sources and the phagophore assembly site (PAS). Thus, Atg9 may play an important role as a membrane...
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