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Article

Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects.

Journal of gastroenterology - 1 Jan 2013

Arisawa Tomiyasu, Tahara Tomomitsu, Shiroeda Hisakazu, Minato Takahiro, Matsue Yasuhiro, Saito Takashi, Fukuyama Tomoki, Otsuka Toshimi, Fukumura Atsushi, Nakamura Masakatsu, Shibata Tomoyuki

Abstract excerpt

BACKGROUND: Visceral sensory impulses are transmitted via C-fibers from the gastrointestinal tract to the central nervous system. The tetrodotoxinresistant (TTX-r) sodium channel, Na(V) 1.8/SNS (sensory-neuron specific), encoded by SCN10A, has been identified on C-fibers. We attempted to clarify the association between functional dyspepsia (FD) and SCN10A non-synonymous polymorphisms (2884 A>G, 3218 C>T and 3275...

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PMID: 22618805
DOI: 10.1007/s00535-012-0602-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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