Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan.

doi:10.1007/s00535-012-0576-1

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Article

Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan.

Journal of gastroenterology - 1 Oct 2012

Arisawa Tomiyasu, Tahara Tomomitsu, Fukuyama Tomoki, Hayashi Ranji, Matsunaga Kazuhiro, Hayashi Nobuhiko, Nakamura Masakatsu, Toshikuni Nobuyuki, Shiroeda Hisakazu, Shibata Tomoyuki

Abstract excerpt

BACKGROUND: The role of genetics in the susceptibility to functional dyspepsia (FD) remains unclear. We attempted to clarify the association between FD and polymorphisms in SLC6A4. In addition, rs5981521 (C>T) in the pri-microRNA 325 (pri-miR-325) coding region was also investigated. METHODS: The study was performed in 395 subjects (172 with no upper abdominal symptoms and 223 with FD, including...

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PMID: 22438098
DOI: 10.1007/s00535-012-0576-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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