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Article

Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.

Journal of clinical gastroenterology - 1 Jan 2010

Tahara Tomomitsu, Shibata Tomoyuki, Nakamura Masakatsu, Yamashita Hiromi, Yoshioka Daisuke, Hirata Ichiro, Arisawa Tomiyasu

Abstract excerpt

OBJECTIVES: Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed...

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Source

Identifiers

PMID: 19770677
DOI: 10.1097/MCG.0b013e3181b5745e

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19770677-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.PMID 19770677Read ↗

Functional dyspepsia susceptibility is related to CD14, GNB3, MIF, and TRPV1 gene polymorphisms in the Greek population.Semantic proximity Read ↗

Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan.Semantic proximity Read ↗

The Role of Ion Channels in Functional Gastrointestinal Disorders (FGID): Evidence of Channelopathies and Potential Avenues for Future Research and Therapeutic TargetsSemantic proximity Read ↗

Gene polymorphisms associated with functional dyspepsia.Semantic proximity Read ↗

Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects.Semantic proximity Read ↗

Association between single nucleotide polymorphisms of the transient receptor potential vanilloid 1 (TRPV-1) gene and patients with irritable bowel syndrome in Korean populations.Semantic proximity Read ↗

Effect of single-nucleotide polymorphisms in TRPV1 on burning pain and capsaicin sensitivity in Japanese adults.Semantic proximity Read ↗

A prospective study on symptom generation according to spicy food intake and TRPV1 genotypes in functional dyspepsia patients.Semantic proximity Read ↗

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779 TC of CCK-1 intron 1 is associated with postprandial syndrome (PDS) in Japanese male subjects.Semantic proximity Read ↗

Functional effects of nonsynonymous polymorphisms in the human TRPV1 gene.Semantic proximity Read ↗

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