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Article

Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.

Journal of clinical gastroenterology - 1 Jan 2010

Tahara Tomomitsu, Shibata Tomoyuki, Nakamura Masakatsu, Yamashita Hiromi, Yoshioka Daisuke, Hirata Ichiro, Arisawa Tomiyasu

Abstract excerpt

OBJECTIVES: Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed to investigate the effect of TRPV1 G315C polymorphism on functional dyspepsia (FD) in a Japanese population. METHODS:...

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Source

Identifiers

PMID: 19770677
DOI: 10.1097/MCG.0b013e3181b5745e

Genes

TRPV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Homozygous TRPV1 315C influences the susceptibility to functional dyspepsia.PMID 19770677Read ↗

Functional dyspepsia susceptibility is related to CD14, GNB3, MIF, and TRPV1 gene polymorphisms in the Greek population.Semantic proximity Read ↗

Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan.Semantic proximity Read ↗

The Role of Ion Channels in Functional Gastrointestinal Disorders (FGID): Evidence of Channelopathies and Potential Avenues for Future Research and Therapeutic TargetsSemantic proximity Read ↗

Gene polymorphisms associated with functional dyspepsia.Semantic proximity Read ↗

Genetic polymorphisms of SCN10A are associated with functional dyspepsia in Japanese subjects.Semantic proximity Read ↗

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