Article
The hybrid recombinational repair pathway operates in a χ activity deficient recC1004 mutant of Escherichia coli.
Biochimie - 1 Sept 2012
Vlašić Ignacija, Simatović Ana, Brčić-Kostić Krunoslav
Abstract excerpt
Homologous recombination is a crucial process for the maintenance of genome integrity. The two main recombination pathways in Escherichia coli (RecBCD and RecF) differ in the initiation of recombination. The RecBCD enzyme is the only component of the RecBCD pathway which acts in the initiation of recombination, and possesses all biochemical activities (helicase, 5'-3' exonuclease, χ cutting and loading of the...
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