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Article

S262A mutation abolishes protective effects of connexin 43 against hypothermic preservation-induced injury in cardiomyocytes.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Jun 2012

Xu He-jing, Chen Wen-liang, Wang Yang, Zheng Ming-zhi, Chen Ying-ying, Shen Yue-liang

Abstract excerpt

BACKGROUND: Alleviation of cold preservation-induced injury is a critical part of the heart transplantation process. In this study we investigate the protective effect of connexin 43 (Cx43) overexpression against hypothermic preservation-induced injury in cardiomyocytes. METHODS: Total RNA was prepared from H9c2 cells using TRIzol reagent to construct a recombinant vector pEGFP-c1-Cx43, which was then transformed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22608771
DOI: 10.1016/j.healun.2012.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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