Article
Effective Hypothermic Storage of Human Pluripotent Stem Cell-Derived Cardiomyocytes Compatible With Global Distribution of Cells for Clinical Applications and Toxicology Testing.
Stem cells translational medicine - 1 May 2016
Correia Cláudia, Koshkin Alexey, Carido Madalena, Espinha Nuno, Šarić Tomo, Lima Pedro A, Serra Margarida, Alves Paula M
Abstract excerpt
UNLABELLED: To fully explore the potential of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), efficient methods for storage and shipment of these cells are required. Here, we evaluated the feasibility to cold store monolayers and aggregates of functional CMs obtained from different PSC lines using a fully defined clinical-compatible preservation formulation and investigated the time frame that...
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