A novel epithelial cell from neonatal rat lung: isolation and differentiated phenotype.

doi:10.1152/ajplung.1990.259.6.L415

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Article

A novel epithelial cell from neonatal rat lung: isolation and differentiated phenotype.

The American journal of physiology - 1 Dec 1990

Roberts P E, Phillips D M, Mather J P

Abstract excerpt

A novel epithelial cell from normal neonatal rat lung has been isolated, established, and maintained for multiple passages in the absence of serum, without undergoing crisis or senescence. By careful manipulation of the nutrition/hormonal microenvironment, we have been able to select, from a heterogeneous population, a single epithelial cell type that can maintain highly differentiated features in vitro. This...

Topics

Actin Cytoskeleton
Animals
Animals, Newborn
Cell Differentiation
Cell Division
Cell Line
Cell Separation
Cells, Cultured
Culture Media
Cytoskeletal Proteins
Desmosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Epithelial Cells

Epithelium

Fluorescent Antibody Technique

Lung

Male

Microscopy, Electron

Phenotype

Source

Open in PubMed

Identifiers

PMID: 2260675
DOI: 10.1152/ajplung.1990.259.6.L415

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2260675-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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