Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation.

Human molecular genetics - 1 Nov 2013

Bian Li, Traurig Michael, Hanson Robert L, Marinelarena Alejandra, Kobes Sayuko, Muller Yunhua L, Malhotra Alka, Huang Ke, Perez Jessica, Gale Alex, Knowler William C, Bogardus Clifton, Baier Leslie J

Abstract excerpt

To identify genes that affect body mass index (BMI) in American Indians who are predominately of Pima Indian heritage, we previously completed a genome-wide association study in 1120 American Indians. That study also included follow-up genotyping for 9 SNPs in 2133 additional subjects. A comprehensive follow-up study has subsequently been completed where 292 SNPs were genotyped in 3562 subjects, of which 128 SNPs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Adipocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Body Mass Index

Share to Body Weight

Share to Hypothalamus

Share to Indians, North American

Share to Inflammation

Share to Longitudinal Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 23825110
DOI: 10.1093/hmg/ddt291
PMCID: PMC3792696

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation.PMID 23825110Read ↗

Multifaceted genome-wide study identifies novel regulatory loci for body mass index in IndiansSemantic proximity Read ↗

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.Semantic proximity Read ↗

Multifaceted genome-wide study identifies novel regulatory loci in SLC22A11 and ZNF45 for body mass index in Indians.Semantic proximity Read ↗

A genome-wide association study of BMI in American Indians.Semantic proximity Read ↗

Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans.Semantic proximity Read ↗

Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals.Semantic proximity Read ↗

Identification and characterization of the long non-coding RNA NFIA-AS2 as a novel locus for body mass index in American Indians.Semantic proximity Read ↗

Functional characterization of a novel p.Ser76Thr variant in IGFBP4 that associates with body mass index in American Indians.Semantic proximity Read ↗

Genome wide association study: searching for genes underlying body mass index in the Chinese.Semantic proximity Read ↗

Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.Semantic proximity Read ↗

<i>Keratinocyte-Associated Protein 3</i> is a novel gene for adiposity with differential effects in males and femalesSemantic proximity Read ↗

The MAP2K5-linked SNP rs2241423 is associated with BMI and obesity in two cohorts of Swedish and Greek children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.