Article
Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.
Human molecular genetics - 1 Sept 2013
Graff Mariaelisa, Ngwa Julius S, Workalemahu Tsegaselassie, Homuth Georg, Schipf Sabine, Teumer Alexander, Völzke Henry, Wallaschofski Henri, Abecasis Goncalo R, Edward Lakatta, Francesco Cucca, Sanna Serena, Scheet Paul, Schlessinger David, Sidore Carlo, Xiao Xiangjun, Wang Zhaoming, Chanock Stephen J, Jacobs Kevin B, Hayes Richard B, Hu Frank, Van Dam Rob M, Crout Richard J, Marazita Mary L, Shaffer John R, Atwood Larry D, Fox Caroline S, Heard-Costa Nancy L, White Charles, Choh Audrey C, Czerwinski Stefan A, Demerath Ellen W, Dyer Thomas D, Towne Bradford, Amin Najaf, Oostra Ben A, Van Duijn Cornelia M, Zillikens M Carola, Esko Tõnu, Nelis Mari, Nikopensius Tit, Metspalu Andres, Strachan David P, Monda Keri, Qi Lu, North Kari E, Cupples L Adrienne, Gordon-Larsen Penny, Berndt Sonja I
Abstract excerpt
Genetic loci for body mass index (BMI) in adolescence and young adulthood, a period of high risk for weight gain, are understudied, yet may yield important insight into the etiology of obesity and early intervention. To identify novel genetic loci and examine the influence of known loci on BMI during this critical time period in late adolescence and early adulthood, we performed a two-stage meta-analysis using 14...
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