Article
Genome wide association study identifies KCNMA1 contributing to human obesity.
BMC medical genomics - 28 Jun 2011
Jiao Hong, Arner Peter, Hoffstedt Johan, Brodin David, Dubern Beatrice, Czernichow Sébastien, van't Hooft Ferdinand, Axelsson Tomas, Pedersen Oluf, Hansen Torben, Sørensen Thorkild I A, Hebebrand Johannes, Kere Juha, Dahlman-Wright Karin, Hamsten Anders, Clement Karine, Dahlman Ingrid
Abstract excerpt
BACKGROUND: Recent genome-wide association (GWA) analyses have identified common single nucleotide polymorphisms (SNPs) that are associated with obesity. However, the reported genetic variation in obesity explains only a minor fraction of the total genetic variation expected to be present in the population. Thus many genetic variants controlling obesity remain to be identified. The aim of this study was to use...
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