Article
Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation.
Endocrinology - 1 Jul 2012
Lu Xiaodan, Ji Yan, Zhang Luqing, Zhang Yuntao, Zhang Shuzhi, An Yao, Liu Peng, Zheng Yaowu
Abstract excerpt
Adipose tissues are classified into white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is responsible for energy storage, and malfunction is associated with obesity. BAT, on the contrary, consumes fat to generate heat through uncoupling mitochondrial respiration and is important in body weight control. Vascular endothelial growth factor (VEGF)-A is the founding member of the VEGF family and has been...
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