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Article

Glucocorticoids Suppress the Browning of Adipose Tissue via miR-19b in Male Mice.

Endocrinology - 1 Jan 2018

Lv Yi-Fan, Yu Jing, Sheng Yun-Lu, Huang Min, Kong Xiao-Cen, Di Wenj-Juan, Liu Juan, Zhou Hong, Liang Hui, Ding Guo-Xian

Abstract excerpt

Physiological levels of glucocorticoids (GCs) are required for proper metabolic control, and excessive GC action has been linked to a variety of pandemic metabolic diseases. MicroRNA (miRNA)-19b plays a critical role in the pathogenesis of GC-induced metabolic diseases. This study explored the potential of miRNA-based therapeutics targeting adipose tissue. Our results showed that overexpressed miR-19b in stromal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29077919
DOI: 10.1210/en.2017-00566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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