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Article

Negative Regulators of Brown Adipose Tissue (BAT)‐Mediated Thermogenesis

8 May 2014

Abstract excerpt

Brown adipose tissue (BAT) is specialized for energy expenditure, a process called adaptive thermogenesis. PET-CT scans recently demonstrated the existence of metabolically active BAT in adult humans, which revitalized our interest in BAT. Increasing the amount and/or activity of BAT holds tremendous promise for the treatment of obesity and its associated diseases. PGC1α is the master regulator of UCP1-mediated...

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PMID: 24809334
DOI: 10.1002/jcp.24664

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