Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in mice

11 Aug 2016

Abstract excerpt

Obesity comprises great risks for human health, contributing to the development of other diseases such as metabolic syndrome, type 2 diabetes and cardiovascular disease. Previously, obese patients were found to have elevated serum levels of VEGF-C, which correlated with worsening of lipid parameters. We recently identified that neutralization of VEGF-C and -D in the subcutaneous adipose tissue during the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Angiogenesis and VEGF in Cancer
Share to Lymphatic System and Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27511834
DOI: 10.1038/srep31566

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic overexpression of VEGF-C induces weight gain and insulin resistance in micePMID 27511834Read ↗

Dichotomous effects of VEGF-A on adipose tissue dysfunction.Semantic proximity Read ↗

Role of VEGFs in metabolic disorders.Semantic proximity Read ↗

Resistance to obesity by repression of VEGF gene expression through induction of brown-like adipocyte differentiation.Semantic proximity Read ↗

A transgenic model of visceral obesity and the metabolic syndromeSemantic proximity Read ↗

Visceral Adipose Tissue-directed Human Kallistatin Gene Therapy Improves Adipose Tissue Remodeling and Metabolic Health in Obese MiceSemantic proximity Read ↗

The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice.Semantic proximity Read ↗

Lack of cardiac and high-fat diet induced metabolic phenotypes in two independent strains of Vegf-b knockout mice.Semantic proximity Read ↗

PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in ObesitySemantic proximity Read ↗

Targeting the IKKβ/mTOR/VEGF Signaling Pathway as a Potential Therapeutic Strategy for Obesity-Related Breast CancerSemantic proximity Read ↗

FOXC2 controls Ang-2 expression and modulates angiogenesis, vascular patterning, remodeling, and functions in adipose tissue.Semantic proximity Read ↗

VEGF and VEGFB Play Balancing Roles in Adipose Differentiation, Gene Expression, and FunctionSemantic proximity Read ↗

Endothelial autophagy-related gene 7 contributes to high fat diet-induced obesitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.