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Article

Short Communication: Methamphetamine Treatment Increases <i>in Vitro</i> and <i>in Vivo</i> HIV Replication

1 Nov 2009

Abstract excerpt

To delineate the mechanistic basis for the epidemiological association between methamphetamine use and accelerated progression to AIDS, we evaluated the direct in vitro and in vivo effects of methamphetamine on HIV-1 replication. Methamphetamine administration significantly increased HIV-1 production by both HIV-infected monocytes and CD4 T lymphocytes in vitro. In addition, in vivo methamphetamine treatment...

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Identifiers

PMID: 19895343
DOI: 10.1089/aid.2008.0282

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