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Article

Genome-wide association of pericardial fat identifies a unique locus for ectopic fat.

PLoS genetics - 1 Jan 2012

Fox Caroline S, White Charles C, Lohman Kurt, Heard-Costa Nancy, Cohen Paul, Zhang Yingying, Johnson Andrew D, Emilsson Valur, Liu Ching-Ti, Chen Y-D Ida, Taylor Kent D, Allison Matthew, Budoff Matthew, Rotter Jerome I, Carr J Jeffrey, Hoffmann Udo, Ding Jingzhong, Cupples L Adrienne, Liu Yongmei

Abstract excerpt

Pericardial fat is a localized fat depot associated with coronary artery calcium and myocardial infarction. We hypothesized that genetic loci would be associated with pericardial fat independent of other body fat depots. Pericardial fat was quantified in 5,487 individuals of European ancestry from the Framingham Heart Study (FHS) and the Multi-Ethnic Study of Atherosclerosis (MESA). Genotyping was performed using...

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Source

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Identifiers

PMID: 22589742
DOI: 10.1371/journal.pgen.1002705
PMCID: PMC3349742

Genes

TRIB2
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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