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Genome‐Wide Association Study of Pericardial Fat Area in 28 161 UK Biobank Participants

27 Oct 2023

Abstract excerpt

BACKGROUND Pericardial adipose tissue (PAT) is the visceral adipose tissue compartment surrounding the heart. Experimental and observational research has suggested that greater PAT deposition might mediate cardiovascular disease, independent of general or subcutaneous adiposity. We characterize the genetic architecture of adiposity‐adjusted PAT and identify causal associations between PAT and adverse cardiac...

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PMID: 37889180
DOI: 10.1161/jaha.123.030661

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