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Article

Alterations of social interaction through genetic and environmental manipulation of the 22q11.2 gene Sept5 in the mouse brain.

Human molecular genetics - 1 Aug 2012

Harper Kathryn M, Hiramoto Takeshi, Tanigaki Kenji, Kang Gina, Suzuki Go, Trimble William, Hiroi Noboru

Abstract excerpt

Social behavior dysfunction is a symptomatic element of schizophrenia and autism spectrum disorder (ASD). Although altered activities in numerous brain regions are associated with defective social cognition and perception, the causative relationship between these altered activities and social cognition and perception-and their genetic underpinnings-are not known in humans. To address these issues, we took...

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Identifiers

PMID: 22589251
DOI: 10.1093/hmg/dds180
PMCID: PMC3392117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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