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Article

Screening for germline EGFR T790M mutations through lung cancer genotyping.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Jun 2012

Oxnard Geoffrey R, Miller Vincent A, Robson Mark E, Azzoli Christopher G, Pao William, Ladanyi Marc, Arcila Maria E

Abstract excerpt

INTRODUCTION: The study of patients carrying germline epidermal [corrected] growth factor receptor (EGFR) mutations, which have been found in cases of familial lung adenocarcinoma, could provide unique insight into lung cancer risk and carcinogenesis in never-smokers. However, investigations into the biology of germline EGFR mutations have been hampered by the lack of an effective strategy for screening for...

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Identifiers

PMID: 22588155
DOI: 10.1097/JTO.0b013e318250ed9d
PMCID: PMC3354706

Genes

EGFR

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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