Article
[Current topics in mutations in the cancer genome].
Nihon Geka Gakkai zasshi - 1 Mar 2012
Iwaya Takeshi, Mimori Koshi, Wakabayashi Go
Abstract excerpt
Several oncogenes and tumor suppressor genes are involved in the multistep process of carcinogenesis in many cancer types. Recently, global mutational analyses have revealed that the cancer genome has far greater numbers of mutations than previously thought. Furthermore, the next-generation sequencing method, which has a different principle from conventional Sanger sequencing, has provided more information on the...
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