Article
Bone marrow-derived cells contribute to cell turnover in aging murine hearts.
International journal of molecular medicine - 1 Aug 2012
Szardien Sebastian, Nef Holger M, Troidl Christian, Willmer Matthias, Voss Sandra, Liebetrau Christoph, Hoffmann Jedrzej, Rolf Andreas, Rixe Johannes, Elsässer Albrecht, Hamm Christian W, Möllmann Helge
Abstract excerpt
The paradigm that cardiac myocytes are non-proliferating, terminally differentiated cells was recently challenged by studies reporting the ability of bone marrow-derived cells (BMCs) to differentiate into cardiomyocytes after myocardial damage. However, little knowledge exists about the role of BMCs in the heart during physiological aging. Twelve-week-old mice...
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