Article
NDM29, a RNA polymerase III-dependent non coding RNA, promotes amyloidogenic processing of APP and amyloid β secretion.
Biochimica et biophysica acta - 1 Jul 2012
Massone Sara, Ciarlo Eleonora, Vella Serena, Nizzari Mario, Florio Tullio, Russo Claudio, Cancedda Ranieri, Pagano Aldo
Abstract excerpt
Neuroblastoma Differentiation Marker 29 (NDM29) is a RNA polymerase (pol) III-transcribed non-coding (nc) RNA whose synthesis drives neuroblastoma (NB) cell differentiation to a nonmalignant neuron-like phenotype. Since in this process a complex pattern of molecular changes is associated to plasma membrane protein repertoire we hypothesized that the expression of NDM29 might influence also key players of...
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