Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of hepatoma-derived growth factor suppresses the malignant phenotype of U87 human glioma cells.

Oncology reports - 1 Jul 2012

Zhang Aixia, Long Weiguo, Guo Ze, Guo Zhenying, Cao Brian B

Abstract excerpt

Hepatoma-derived growth factor (HDGF) has been shown to correlate with increased malignancy of different types of tumors and could be an independent prognostic index for human cancers. We previously found that HDGF is overexpressed in glioma tissues and that its expression level may correlate with the clinical pathological grade. In the present study, we investigated the effects of HDGF downregulation on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Down-Regulation
Share to Glioma
Share to Intercellular Signaling Peptides and Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Nude

Share to Neoplasm Invasiveness

Share to Neoplasm Transplantation

Share to RNA Interference

Share to Tumor Burden

Source

Identifiers

PMID: 22576797
DOI: 10.3892/or.2012.1768

Genes

HDGF
HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of hepatoma-derived growth factor suppresses the malignant phenotype of U87 human glioma cells.PMID 22576797Read ↗

Hepatoma-Derived Growth Factor: An Overview and Its Role as a Potential Therapeutic Target Molecule for Digestive MalignanciesSemantic proximity Read ↗

Clinical and biological significance of hepatoma‐derived growth factor in Ewing's sarcomaSemantic proximity Read ↗

HDGF: A Novel Jack-of-All-Trades in CancerSemantic proximity Read ↗

miR-663a inhibits hepatocellular carcinoma cell proliferation and invasion by targeting HMGA2.Semantic proximity Read ↗

Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma modelSemantic proximity Read ↗

RNAi-mediated knockdown of E2F2 inhibits tumorigenicity of human glioblastoma cellsSemantic proximity Read ↗

Differentiation therapy of hepatocellular carcinoma in mice with recombinant adenovirus carrying hepatocyte nuclear factor-4α geneSemantic proximity Read ↗

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway.Semantic proximity Read ↗

BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasivenessSemantic proximity Read ↗

Involvement of microRNA-718, a new regulator of EGR3, in regulation of malignant phenotype of HCC cells.Semantic proximity Read ↗

Recombinant adenovirus carrying the hepatocyte nuclear factor-1alpha gene inhibits hepatocellular carcinoma xenograft growth in miceSemantic proximity Read ↗

Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.