Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasiveness

12 Jul 2017

Abstract excerpt

The chromatin remodeler complex SWI/SNF plays an important role in physiological and pathological processes. Brahma related gene 1(BRG1), a catalytic subunit of the SWI/SNF complex, is known to be mutated in hepatocellular carcinoma (HCC). However, its role in HCC remains unclear. Here, we investigate the role of BRG1 on cell growth and invasiveness as well as its effect on the expression of putative target...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28700662
DOI: 10.1371/journal.pone.0180225

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRG1 promotes hepatocarcinogenesis by regulating proliferation and invasivenessPMID 28700662Read ↗

Oncogene-dependent function of BRG1 in hepatocarcinogenesisSemantic proximity Read ↗

Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expressionSemantic proximity Read ↗

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.Semantic proximity Read ↗

BRG1 Is a Prognostic Marker and Potential Therapeutic Target in Human Breast CancerSemantic proximity Read ↗

Regulation of PTEN expression by the SWI/SNF chromatin-remodelling protein BRG1 in human colorectal carcinoma cellsSemantic proximity Read ↗

BRG1 promotes VEGF-A expression and angiogenesis in human colorectal cancer cellsSemantic proximity Read ↗

The BRG1 ATPase of Human SWI/SNF Chromatin Remodeling Enzymes as a Driver of CancerSemantic proximity Read ↗

BRD4 promotes tumor growth and epithelial-mesenchymal transition in hepatocellular carcinomaSemantic proximity Read ↗

Brahma-Related Gene-1 (BRG1) promotes the malignant phenotype of glioblastoma cells.Semantic proximity Read ↗

ASF1B Serves as a Potential Therapeutic Target by Influencing Cell Cycle and Proliferation in Hepatocellular CarcinomaSemantic proximity Read ↗

BRG1/SMARCA4 Inactivation Promotes Non–Small Cell Lung Cancer Aggressiveness by Altering Chromatin OrganizationSemantic proximity Read ↗

Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer developmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.