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Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model

25 Mar 2008

Abstract excerpt

Human mesenchymal stem cells (hMSCs) can home to tumor sites and inhibit the growth of tumor cells. Little is known about the underlying molecular mechanisms that link hMSCs to the targeted inhibition of tumor cells. In this study, we investigated the effects of hMSCs on two human hepatoma cell lines (H7402 and HepG2) using an animal transplantation model, a co-culture system and conditioned media from hMSCs....

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PMID: 18364678
DOI: 10.1038/cr.2008.40

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