Article
miR-663a inhibits hepatocellular carcinoma cell proliferation and invasion by targeting HMGA2.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jul 2016
Huang Weizhen, Li Jun, Guo Xiaohong, Zhao Yingchu, Yuan Xia
Abstract excerpt
Hepatocellular carcinoma (HCC) is a highly aggressive solid malignancy throughout the world. Dysregulation of miRNAs play essential roles in HCC progression via aberrant regulation of cell proliferation, apoptosis, as well as metastasis. miR-663a is a poorly investigated miRNA. Whether miR-663a regulates HCC development remains unknown. The aim of the study was to explore the role of miR-663a in HCC development....
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