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Article

FBXW7: a critical tumor suppressor of human cancers.

Molecular cancer - 7 Aug 2018

Yeh Chien-Hung, Bellon Marcia, Nicot Christophe

Abstract excerpt

The ubiquitin-proteasome system (UPS) is involved in multiple aspects of cellular processes, such as cell cycle progression, cellular differentiation, and survival (Davis RJ et al., Cancer Cell 26:455-64, 2014; Skaar JR et al., Nat Rev Drug Discov 13:889-903, 2014; Nakayama KI and Nakayama K, Nat Rev Cancer 6:369-81, 2006). F-box and WD repeat domain containing 7 (FBXW7), also known as Sel10, hCDC4 or hAgo, is a...

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Identifiers

PMID: 30086763
DOI: 10.1186/s12943-018-0857-2
PMCID: PMC6081812

Genes

AURKA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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