Article
Vascular mural cells in healing canine myocardial infarcts.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Aug 2004
Dobaczewski Marcin, Akrivakis Spyridon, Nasser Kamal, Michael Lloyd H, Entman Mark L, Frangogiannis Nikolaos G
Abstract excerpt
Angiogenesis is a critical process in healing of myocardial infarcts, leading to the formation of highly vascular granulation tissue. However, effective cardiac repair depends on mechanisms that inhibit the angiogenic process after a mature scar is formed, preventing inappropriate expansion of the fibrotic process. Using a canine model of reperfused myocardial infarction, we demonstrated that maturation of the...
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