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Article

Comparative processing and function of human and ferret cystic fibrosis transmembrane conductance regulator.

The Journal of biological chemistry - 22 Jun 2012

Fisher John T, Liu Xiaoming, Yan Ziying, Luo Meihui, Zhang Yulong, Zhou Weihong, Lee Ben J, Song Yi, Guo Chenhong, Wang Yujiong, Lukacs Gergely L, Engelhardt John F

Abstract excerpt

The most common cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation is ΔF508, and this causes cystic fibrosis (CF). New CF models in the pig and ferret have been generated that develop lung, pancreatic, liver, and intestinal pathologies that reflect disease in CF patients. Sp...

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Source

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Identifiers

PMID: 22570484
DOI: 10.1074/jbc.M111.336537
PMCID: PMC3381131

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22570484-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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