Article
Understanding the determinants of exceptional longevity.
Annals of internal medicine - 2 Sept 2003
Perls Thomas, Terry Dellara
Abstract excerpt
Centenarians represent an extreme of life expectancy. They achieve their exceptional longevity in part by lacking genetic variations linked to premature death. Pedigree studies have shown a substantial familial component in the ability to survive to extreme old age, and a recent study demonstrated a locus on chromosome 4 linked to exceptional longevity, indicating the likely existence of at least one...
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