Article
Elucidating the mitochondrial proteome of Toxoplasma gondii reveals the presence of a divergent cytochrome c oxidase.
eLife - 11 Sept 2018
Seidi Azadeh, Muellner-Wong Linden S, Rajendran Esther, Tjhin Edwin T, Dagley Laura F, Aw Vincent Yt, Faou Pierre, Webb Andrew I, Tonkin Christopher J, van Dooren Giel G
Abstract excerpt
The mitochondrion of apicomplexan parasites is critical for parasite survival, although the full complement of proteins that localize to this organelle has not been defined. Here we undertake two independent approaches to elucidate the mitochondrial proteome of the apicomplexan Toxoplasma gondii. We identify approximately 400 mitochondrial proteins, many of which lack homologs in the animals that these parasites...
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