Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is the mitochondrion a promising drug target in trypanosomatids?

1 Jan 2022

Abstract excerpt

The trypanosomatids Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are etiological agents of important neglected tropical diseases, affecting millions of people worldwide, and the drugs available for these diseases present several limitations. Novel efficient and nontoxic drugs are necessary as an alternative to the current chemotherapy. The unique mitochondrion of trypanosomatids and its peculiar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Parasites and Host Interactions
Share to Research on Leishmaniasis Studies
Share to Trypanosoma species research and implications

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35195164
DOI: 10.1590/0074-02760210379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 21 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is the mitochondrion a promising drug target in trypanosomatids?PMID 35195164Read ↗

The Double-Edged Sword in Pathogenic Trypanosomatids: The Pivotal Role of Mitochondria in Oxidative Stress and BioenergeticsSemantic proximity Read ↗

Mitochondrial Drug Targets in Apicomplexan ParasitesSemantic proximity Read ↗

Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death.Semantic proximity Read ↗

Parasite powerhouse: A review of the Toxoplasma gondii mitochondrionSemantic proximity Read ↗

Iron metabolism in trypanosomatids, and its crucial role in infectionSemantic proximity Read ↗

Targeting Channels and Transporters in Protozoan Parasite InfectionsSemantic proximity Read ↗

Is the Mitochondrion a Good Malaria Drug Target?Semantic proximity Read ↗

Trypanosomatids: Odd Organisms, Devastating DiseasesSemantic proximity Read ↗

Biosynthetic Pathways of Plastid-Derived Organelles as Potential Drug Targets Against Parasitic ApicomplexaSemantic proximity Read ↗

The trypanothione system and the opportunities it offers to create drugs for the neglected kinetoplast diseasesSemantic proximity Read ↗

Targeting Trypanothione Metabolism in Trypanosomatid Human ParasitesSemantic proximity Read ↗

Cellular and Molecular Targets of Nucleotide-Tagged Trithiolato-Bridged Arene Ruthenium Complexes in the Protozoan Parasites Toxoplasma gondii and Trypanosoma bruceiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.