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Article

Mitochondrial dual-coding genes in Trypanosoma brucei.

PLoS neglected tropical diseases - 1 Oct 2017

Kirby Laura E, Koslowsky Donna

Abstract excerpt

Trypanosoma brucei is transmitted between mammalian hosts by the tsetse fly. In the mammal, they are exclusively extracellular, continuously replicating within the bloodstream. During this stage, the mitochondrion lacks a functional electron transport chain (ETC). Successful transition to the fly, requires activation of the ETC and ATP synthesis via oxidative phosphorylation. This life cycle leads to a major...

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Identifiers

PMID: 28991908
DOI: 10.1371/journal.pntd.0005989
PMCID: PMC5650466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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