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Article

Genome abnormalities precede prostate cancer and predict clinical relapse.

The American journal of pathology - 1 Jun 2012

Yu Yan P, Song Chi, Tseng George, Ren Bao Guo, LaFramboise William, Michalopoulos George, Nelson Joel, Luo Jian-Hua

Abstract excerpt

The prediction of prostate cancer clinical outcome remains a major challenge after the diagnosis, even with improved early detection by prostate-specific antigen (PSA) monitoring. To evaluate whether copy number variation (CNV) of the genomes in prostate cancer tumor, in benign prostate tissues adjacent to the tumor (AT), and in the blood of patients with prostate cancer predicts biochemical (PSA) relapse and the...

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Source

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Identifiers

PMID: 22569189
DOI: 10.1016/j.ajpath.2012.03.008
PMCID: PMC3385611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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