Article
Genomic Copy Number Variations in the Genomes of Leukocytes Predict Prostate Cancer Clinical Outcomes.
PloS one - 1 Jan 2015
Yu Yan P, Liu Silvia, Huo Zhiguang, Martin Amantha, Nelson Joel B, Tseng George C, Luo Jian-Hua
Abstract excerpt
Accurate prediction of prostate cancer clinical courses remains elusive. In this study, we performed whole genome copy number analysis on leukocytes of 273 prostate cancer patients using Affymetrix SNP6.0 chip. Copy number variations (CNV) were found across all chromosomes of the human genome. An average of 152 CNV fragments per genome was identified in the leukocytes from prostate cancer patients. The size...
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