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Article

Altered MicroRNA Expression Profile in Human Pituitary GH Adenomas: Down-Regulation of miRNA Targeting HMGA1, HMGA2, and E2F1

8 May 2012

Abstract excerpt

CONTEXT: MicroRNA (miRNA) are an important class of regulators of gene expression. Altered miRNA expression has been constantly found in human neoplasias and plays an important role in the process of carcinogenesis. OBJECTIVE: The aim of this study was to identify specific miRNA whose expression is altered in GH-secreting pituitary adenomas. DESIGN: Using a miRNACHIP microarray, we have analyzed the miRNA...

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PMID: 22564666
DOI: 10.1210/jc.2011-3482

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