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Article

Critical role of the HMGA2 gene in pituitary adenomas.

Cell cycle (Georgetown, Tex.) - 1 Sept 2006

Fedele Monica, Pierantoni Giovanna Maria, Visone Rosa, Fusco Alfredo

Abstract excerpt

The molecular pathway leading to pituitary tumorigenesis is still largely unknown and is one of the challenges of the endocrine oncology. The development of pituitary adenomas in HMGA2 transgenic mice and the finding of HMGA2 amplification and overexpression in human pituitary adenomas led us to...

Read the complete abstract on PubMed

Topics

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Share to Adenoma
Share to Cell Transformation, Neoplastic
Share to E2F1 Transcription Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Deacetylase 1

Share to Histone Deacetylases

Share to HMGA2 Protein

Share to Pituitary Neoplasms

Share to Transcriptional Activation

Source

Identifiers

PMID: 16969098
DOI: 10.4161/cc.5.18.3211

Genes

HMGA2
HDAC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16969098-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Critical role of the HMGA2 gene in pituitary adenomas.PMID 16969098Read ↗

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