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Article

MEG3/MIR-376B-3P/HMGA2 axis is involved in pituitary tumor invasiveness

3 Jan 2020

Abstract excerpt

OBJECTIVE: To date, long noncoding RNAs (lncRNAs) have proven to function as key regulators in tumorigenesis. Among these lncRNAs, MEG3 displays low levels in various neoplasms and tumor cell lines. However, the regulatory mechanism of MEG3 and MIR-376B-3P, one of the microRNAs from downstream gene clusters of the DLK1-MEG3 locus, remains insufficiently defined. METHODS: The authors used quantitative real-time...

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PMID: 31899875
DOI: 10.3171/2019.10.jns191959

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