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Article

MicroRNAs Differentially Expressed in ACTH-Secreting Pituitary Tumors

8 Oct 2008

Abstract excerpt

CONTEXT: MicroRNAs (miRNAs) are small noncoding RNAs, functioning as antisense regulators of gene expression by targeting mRNA and contributing to cancer development and progression. More than 50% of miRNA genes are located in cancer-associated genomic regions or in fragile sites of the genome. OBJECTIVE: The aim of the study was to analyze the differential expression of let-7a, miR-15a, miR-16, miR-21, miR-141,...

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Identifiers

PMID: 18840638
DOI: 10.1210/jc.2008-1451

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