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Article

Met signaling regulates growth, repopulating potential and basal cell-fate commitment of mammary luminal progenitors: implications for basal-like breast cancer.

Oncogene - 14 Mar 2013

Gastaldi S, Sassi F, Accornero P, Torti D, Galimi F, Migliardi G, Molyneux G, Perera T, Comoglio P M, Boccaccio C, Smalley M J, Bertotti A, Trusolino L

Abstract excerpt

Basal-like breast cancer is an aggressive subtype of mammary carcinoma. Despite expressing basal markers, typical of mammary stem cells, this tumor has been proposed to originate from luminal progenitors, which are downstream of stem cells along the mammary epithelial hierarchy. This suggests that committed luminal progenitors may reacquire basal, stem-like characteristics, but the mechanisms that regulate this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mammary Glands, Animal

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Source

Identifiers

PMID: 22562252
DOI: 10.1038/onc.2012.154

Genes

HGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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